Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.47 |
| ▸ | GCLC | P48506 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.45 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | ARG2 | P78540 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Buthionine Sulfoxime SCHEMBL9300391 | 1.00 | PMP22 (0.59) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| Buthionine Sulfoxime SCHEMBL115963 | 1.00 | PMP22 (0.59) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| Buthionine Sulfoximine SCHEMBL62033 | 1.00 | PMP22 (0.59) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| Buthionine Sulfoxime SCHEMBL62034 | 1.00 | PMP22 (0.59) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| Buthionine Sulfoxime SCHEMBL121171 | 1.00 | PMP22 (0.59) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| Buthionine Sulfoximine SCHEMBL28249466 | 0.98 | PMP22 (0.58) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| SCHEMBL13746032 | 0.89 | PMP22 (0.63) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| SCHEMBL5904143 | 0.89 | PMP22 (0.63) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| SCHEMBL21965593 | 0.86 | PMP22 (0.50) | PMP22DDAH1GCLCSLC1A2SLC1A1 | |
| SCHEMBL27254997 | 0.86 | PMP22 (0.42) | PMP22DDAH1GCLCSLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123447-A1 | COMPOSITIONS AND METHODS TO INHIBIT RNA VIRAL REPRODUCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-05-14 | — | — | US | disclosed |