⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009074 | 0.78 | — | — | |
| SCHEMBL21206 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL18740686 | 0.73 | — | — | |
| SCHEMBL11098706 | 0.73 | — | — | |
| SCHEMBL28899342 | 0.73 | — | — | |
| SCHEMBL1064256 | 0.73 | — | — | |
| Methyl Alcohol SCHEMBL8440529 | 0.73 | — | — | |
| SCHEMBL11545922 | 0.72 | — | — | |
| SCHEMBL14037955 | 0.72 | — | — | |
| SCHEMBL177587 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | claimed |
| CN-107530351-A | Synthetic rigidin analogs, salts, solvates and prodrugs thereof as anticancer agents and methods of producing the same | 新墨西哥技术研究基金会 | 2018-01-02 | — | — | CN | claimed |
| US-9603829-B2 | HSP90 inhibitors with modified toxicity | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-03-28 | — | — | US | claimed |
| EP-2190291-B1 | HSP90 INHIBITORS WITH MODIFIED TOXICITY | UNIV COLORADO REGENTS (US) | 2015-10-14 | — | — | EP | claimed |
| US-20150225388-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-08-13 | — | — | US | claimed |
| US-20140315845-A1 | HSP90 INHIBITORS WITH MODIFIED TOXICITY | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2014-10-23 | — | — | US | claimed |
| US-8551964-B2 | Hsp90 inhibitors with modified toxicity | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-10-08 | — | — | US | claimed |
| WO-2013074695-A1 | HSP90 INHIBITORS WITH MODIFIED TOXICITY | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-05-23 | — | — | WO | claimed |
| US-20120022011-A1 | HSP90 INHIBITORS WITH MODIFIED TOXICITY | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2012-01-26 | — | — | US | claimed |
| CN-101918371-A | Amide derivatives as sirtuin modulators | SIRTRIS PHARMACEUTICALS INC | 2010-12-15 | — | — | CN | claimed |
| US-20060205705-A1 | Hsp90 inhibitors, methods of making and uses therefor | UNIVERSITY OF COLORADO (US) | 2006-09-14 | — | — | US | claimed |
| US-6936077-B2 | 1,3-diamino-4-(aminomethyl)—benzene derivatives and colorants containing the said compounds | WELLA AG (DE) | 2005-08-30 | — | — | US | claimed |
| EP-1509508-A1 | SELECTIVE CHROMOPHORES | Westman, Gunnar (SE) | 2005-03-02 | — | — | EP | claimed |
| WO-2003104210-A1 | SELECTIVE CHROMOPHORES | CHALMERS TECHNOLOGY LICENSING AB (SE) | 2003-12-18 | — | — | WO | claimed |
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | claimed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | claimed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| US-4008043-A | Diphenylamines for dyeing keratinic fibers | L'OREAL (FR) | 1977-02-15 | — | — | US | claimed |