Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL4292987 | 0.78 | TDP1 (1.00) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL18636497 | 0.78 | TDP1 (1.00) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL17223 | 0.78 | TDP1 (1.00) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL10704793 | 0.78 | TDP1 (1.00) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL30036615 | 0.78 | TDP1 (1.00) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL10999079 | 0.77 | TDP1 (0.84) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL3810753 | 0.76 | TDP1 (0.94) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| Bromide SCHEMBL28859264 | 0.76 | TDP1 (0.94) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| Methane SCHEMBL29110024 | 0.76 | TDP1 (0.94) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 | |
| SCHEMBL28230782 | 0.76 | TDP1 (0.94) | ALDH1A1HSD17B10TDP1APOBEC3GHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557153-B2 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2009-07-07 | — | — | US | disclosed |
| EP-1951788-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007053500-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100059-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-03 | — | — | US | disclosed |