⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956235 | 0.73 | — | — | |
| SCHEMBL5736475 | 0.69 | — | — | |
| SCHEMBL2022949 | 0.65 | — | — | |
| SCHEMBL24119932 | 0.65 | — | — | |
| SCHEMBL15228587 | 0.65 | — | — | |
| Isobutane SCHEMBL5241727 | 0.64 | TSHR (0.33) | — | |
| Propane SCHEMBL28442519 | 0.64 | TSHR (0.33) | — | |
| Propane SCHEMBL28447008 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL21634047 | 0.62 | — | — | |
| SCHEMBL11435509 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045403-B2 | Geranyl geranyl acetone (GGA) derivatives and compositions thereof | COYOTE PHARMACEUTICALS, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20150025077-A1 | GGA AND GGA DERIVATIVES COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM | COYOTE PHARMACEUTICALS, INC. (US) | 2015-01-22 | — | — | US | disclosed |
| WO-2014163643-A1 | GGA AND GGA DERIVATIVES COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM | COYOTE PHARMACEUTICALS, INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014151719-A1 | SUBLINGUAL FORMULATIONS INCLUDING GERANYLGERANYLACETONE AND GERANYLGERANYLACETONE DERIVATIVES | COYOTE PHARMACEUTICALS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20130296323-A1 | GGA AND GGA DERIVATIVES COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM | COYOTE PHARMACEUTICALS, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| WO-2013130654-A1 | GGA AND GGA DERIVATIVES, COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM | COYOTE PHARMACEUTICALS, INC. (US) | 2013-09-06 | — | — | WO | disclosed |
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-1233769-B1 | Imidazole derivatives | SMITHKLINE BEECHAM PLC (GB) | 2007-12-26 | — | — | EP | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| US-7189745-B1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20070010534-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2007-01-11 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| EP-1233769-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2004-12-29 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1233769-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001037835-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2001-05-31 | — | — | WO | disclosed |
| US-4656217-A | CURABLE CARBOXY-CONTAINING POLYMER MODIFIED BY AN UNSATURATED AZIRIDINE COMPOUND; ADHESIVES, CONCRETE SLABS; CASTINGS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1987-04-07 | — | — | US | disclosed |