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SCHEMBL4451066

SCHEMBL4451066

O=C(NC1CCC1)c1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)s2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 4/20 0.52
▸ CNR2 P34972 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153187 0.97 CNR1 (0.52) CNR1
SCHEMBL4149674 0.96 CNR2 (0.51) CNR1CNR2
SCHEMBL4146599 0.93 CNR2 (0.50) CNR1CNR2
SCHEMBL4435064 0.88 CNR2 (0.49) CNR2
SCHEMBL4137991 0.86 CNR2 (0.60) CNR2
SCHEMBL4163014 0.85 CNR2 (0.59) CNR1CNR2
SCHEMBL4145165 0.84 CNR2 (0.61) CNR2
SCHEMBL4445507 0.84 CNR2 (0.52) CNR2
SCHEMBL4163002 0.84 CNR2 (0.60) CNR1CNR2
SCHEMBL4435979 0.84 CNR2 (0.60) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009078498-A1 BIARYLPYRAZOLE 4-CARBOXAMIDES AS CANNABINOID CB1 RECEPTOR LIGANDS GREEN CROSS CORPORATION (KR) 2009-06-25 — — WO disclosed