SCHEMBL4451188

SCHEMBL4451188

CCCCOC(=O)NC(N)=O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.61
MAPT P10636 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
EPHX1 P07099 1/20 0.52
ACHE P22303 14/20 0.50
ALDH1A1 P00352 1/20 0.50
NPC1 O15118 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ATM Q13315 1/20 0.47
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687894 0.94 EPHX1 (0.60) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL16722248 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2184501 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2184904 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2185689 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2185950 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2185919 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2189540 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2185439 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE
SCHEMBL2183309 0.92 EPHX1 (0.63) RAB9AMAPTNPSR1EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356441-B1 BIURET POLYISOCYANATE COMPOSITION VENCOREX FRANCE (FR) 2024-05-22 EP disclosed
CN-113424917-A Sugui fragrant ginger meal replacement powder and preparation method thereof 苏培林 2021-09-24 CN disclosed
CN-108137779-B Biuret polyisocyanate compositions 温科莱斯法国公司 2021-04-20 CN disclosed
US-20190040179-A1 COMPOSITION POLYISOCYANATE BIURET VENCOREX FRANCE (FR) 2019-02-07 US disclosed
CN-105309923-A Health-care food possessing brain-fortifying intelligence-developing function ZHAO RUI 2016-02-10 CN disclosed
CN-103585452-A Traditional Chinese medicinal composition for treating xerophthalmia XIE LIKE 2014-02-19 CN disclosed
CN-102302149-A Multi-panax healthcare food and preparation method thereof RUI ZHAO 2012-01-04 CN disclosed
US-7635742-B2 Crosslinking polyurethanes RHODIA CHIMIE (FR) 2009-12-22 US disclosed
US-7297752-B2 Method for catalytic dimerization of isocyanates RHODIA CHIMIE (FR) 2007-11-20 US disclosed
US-7288213-B1 Method for preparing low viscosity tricondensate polyfunctional isocyanates RHODIA CHIMIE (FR) 2007-10-30 US disclosed
US-20040073046-A1 Modified isocyanates RHODIA CHIMIE (FR) 2004-04-15 US disclosed
EP-1167339-B1 Process for producing dialkyl carbonate MITSUBISHI GAS CHEMICAL CO (JP) 2003-05-02 EP disclosed
US-20030050424-A1 Modified isocyanates RHODIA CHIMIE (FR) 2003-03-13 US disclosed
US-6359163-B2 UTILIZING ALLOPHANATE BY-PRODUCT AS RAW-MATERIAL INSTEAD OF OR WITH UREA; REACTION WITH ALKYL ALCOHOL; WASTE RECYCLING MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 2002-03-19 US disclosed
EP-1167339-A2 Process for producing dialkyl carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-01-02 EP disclosed
US-20010051740-A1 Process for producing dialkyl carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. 2001-12-13 US disclosed