SCHEMBL4452339

SCHEMBL4452339

O=C(Cl)N1c2ccccc2Sc2ccc(Cl)cc21

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.72
ACHE P22303 6/20 0.72
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 2/20 0.61
KDM4E B2RXH2 1/20 0.61
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522271 0.87 BCHE (0.70) BCHEACHEMAPT
SCHEMBL30743852 0.87 BCHE (0.70) BCHEACHEMAPT
SCHEMBL30882096 0.87 BCHE (0.70) BCHEACHEMAPT
SCHEMBL8870414 0.86 NOX1 (0.73) BCHEACHEMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL27211953 0.85 BCHE (0.68) BCHEACHEMAPT
SCHEMBL5239436 0.84 BCHE (0.78) BCHEACHEMEN1KMT2AALDH1A1
SCHEMBL14291953 0.84 BCHE (0.89) BCHEACHEMEN1KMT2AALDH1A1
SCHEMBL28628271 0.84 BCHE (1.00) BCHEACHEMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL2363423 0.83 BCHE (0.66) BCHEACHEMAPT
Hydrochloric Acid SCHEMBL2363425 0.83 BCHE (0.66) BCHEACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535890-B1 METHOD FOR PRODUCING P-DICHLOROBENZENE KUREHA CORP (JP) 2009-05-27 EP disclosed
US-7211704-B2 Method for producing p-dichlorobenzene KUREHA CORPORATION (JP) 2007-05-01 US disclosed
US-20060106264-A1 Method for producing p-dichlorobenzene KUREHA CHEMICAL INDUSTRY COMPANY LIMITED (JP) 2006-05-18 US disclosed
EP-1535890-A1 METHOD FOR PRODUCING P-DICHLOROBENZENE Kureha Chemical Industry Co., Ltd. (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106264-A1 Method for producing p-dichlorobenzene DDT, DCAF15, CLTB BCHE 1230/4885ACHE 3039/4885MEN1 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.