Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 16/20 | 0.60 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4453009 | 0.99 | NSD2 (0.61) | NSD2EDNRATTRTP53 | |
| SCHEMBL4473516 | 0.85 | EDNRA (0.47) | NSD2EDNRATP53 | |
| SCHEMBL4449108 | 0.80 | EDNRA (0.52) | NSD2EDNRATP53 | |
| SCHEMBL4446573 | 0.79 | NSD2 (0.63) | NSD2 | |
| Hydrochloric Acid SCHEMBL4444911 | 0.78 | NSD2 (0.64) | NSD2 | |
| SCHEMBL4443335 | 0.77 | NSD2 (0.78) | NSD2 | |
| Hydrochloric Acid SCHEMBL4446935 | 0.76 | NSD2 (0.78) | NSD2 | |
| SCHEMBL4443339 | 0.76 | NSD2 (0.67) | NSD2 | |
| SCHEMBL4479900 | 0.76 | KMT2A (0.50) | NSD2TP53 | |
| SCHEMBL23092341 | 0.76 | NSD2 (0.66) | NSD2EDNRATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547716-B2 | Sulfonamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-06-16 | — | — | US | claimed |