SCHEMBL4452841

SCHEMBL4452841

CCO[Si](CCCC(S)C(=O)O)(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 3/20 0.44
FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452615 0.84 RNPEP (0.43) RNPEPFOLH1
SCHEMBL8959221 0.83 TDP1 (0.33)
SCHEMBL29066700 0.80 BLM (0.44)
SCHEMBL28139468 0.79 MEN1 (0.33)
SCHEMBL29048433 0.79 TDP1 (0.31)
SCHEMBL4444505 0.77 RNPEP (0.40) RNPEPFOLH1
SCHEMBL15011067 0.76 LCK (0.33)
SCHEMBL475633 0.76 FOLH1 (0.44) FOLH1
SCHEMBL16872466 0.75 CA1 (0.32)
SCHEMBL9859900 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240059800-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2024-02-22 US disclosed
US-20240052139-A1 TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS BRIDGESTONE CORPORATION (JP) 2024-02-15 US disclosed
EP-4263621-A1 TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS BRIDGESTONE CORPORATION (JP) 2023-10-25 EP disclosed
EP-4263567-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2023-10-25 EP disclosed
WO-2022133477-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2022-06-23 WO disclosed
WO-2022133478-A1 TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS BRIDGESTONE CORPORATION (JP) 2022-06-23 WO disclosed
EP-4004100-A1 TEMPERATURE STABLE POLYMERIC BLENDS FOR USE IN NON-PNEUMATIC TIRES Bridgestone Americas Tire Operations, LLC (US) 2022-06-01 EP disclosed
CN-114127188-A Temperature stable polymer blends for non-pneumatic tires 普利司通美国轮胎运营有限责任公司 2022-03-01 CN disclosed
US-11028256-B2 Silica-containing rubber compositions containing specified coupling agents and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-06-08 US disclosed
WO-2021021274-A1 TEMPERATURE STABLE POLYMERIC BLENDS FOR USE IN NON-PNEUMATIC TIRES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-02-04 WO disclosed
US-9951208-B2 Silica shielding agents and related methods BRIDGESTONE CORPORATION (JP) 2018-04-24 US disclosed
US-9758639-B2 Rubber composition with imidazole-based silica shielding agent BRIDGESTONE CORPORATION (JP) 2017-09-12 US disclosed
US-20170247532-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-08-31 US disclosed
EP-2914654-B1 RUBBER COMPOSITIONS COMPRISING METAL CARBOXYLATES AND PROCESSES FOR MAKING THE SAME BRIDGESTONE CORP (JP) 2017-05-31 EP disclosed
US-20160130423-A1 Silica Shielding Agents And Related Methods BRIDGESTONE CORPORATION (JP) 2016-05-12 US disclosed
US-20150315362-A1 RUBBER COMPOSITION WITH IMIDAZOLE-BASED SILICA SHIELDING AGENT BRIDGESTONE CORPORATION (JP) 2015-11-05 US disclosed
US-7592384-B2 Elatomeric composition containing multiple silane coupling agents BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2009-09-22 US disclosed
US-20080161458-A1 Elastomeric composition containing multiple silane coupling agents BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2008-07-03 US disclosed
US-7256231-B2 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION (JP) 2007-08-14 US disclosed
US-20060106143-A1 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION 2006-05-18 US disclosed