Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | TXN | P10599 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347107 | 0.84 | GCGR (0.42) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4462472 | 0.83 | GCGR (0.48) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2344461 | 0.81 | GCGR (0.40) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2342322 | 0.81 | GCGR (0.40) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4449474 | 0.80 | GCGR (0.63) | GCGR | |
| SCHEMBL27885298 | 0.80 | GCGR (0.49) | GCGR | |
| SCHEMBL4455298 | 0.79 | GCGR (0.48) | GCGR | |
| SCHEMBL27885299 | 0.79 | GCGR (0.39) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14315854 | 0.78 | KDM1A (0.47) | GCGRKDM4EALDH1A1 | |
| SCHEMBL27850982 | 0.78 | GCGR (0.43) | GCGRMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009157014-A2 | A PROCESS FOR PREPARING HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |