Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456982 | 0.93 | ADORA2A (0.58) | ADORA2AADORA2BADORA1 | |
| SCHEMBL29448500 | 0.87 | ADORA2A (0.70) | ADORA2AADORA2BADORA1 | |
| SCHEMBL2539375 | 0.87 | ADORA2A (0.70) | ADORA2AADORA2BADORA1 | |
| SCHEMBL2539373 | 0.87 | ADORA2A (0.70) | ADORA2AADORA2BADORA1 | |
| SCHEMBL24305379 | 0.84 | ADORA2A (0.57) | ADORA2AADORA2BADORA1 | |
| SCHEMBL29499431 | 0.83 | GLA (0.58) | ADORA2AADORA2BADORA1 | |
| SCHEMBL24304503 | 0.83 | GLA (0.58) | ADORA2AADORA2BADORA1 | |
| SCHEMBL27123775 | 0.83 | GLA (0.58) | ADORA2AADORA2BADORA1 | |
| SCHEMBL26979963 | 0.83 | GLA (0.72) | ADORA2AADORA2BADORA1 | |
| SCHEMBL27125885 | 0.83 | GLA (0.72) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111231-A2 | METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES | NorthEastern University (US) | 2009-10-28 | — | — | EP | claimed |
| WO-2008147482-A2 | METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES | NORTHEASTERN UNIVERSITY (US) | 2008-12-04 | — | — | WO | claimed |