Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | NCS1 | P62166 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453326 | 1.00 | CSNK1D (0.53) | CSNK1DHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5827952 | 0.89 | CSNK1D (0.56) | CSNK1DHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13408929 | 0.89 | CSNK1D (0.56) | CSNK1DHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4457418 | 0.88 | CSNK1D (0.54) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4457424 | 0.88 | CSNK1D (0.54) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4457168 | 0.87 | CSNK1D (0.53) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4457160 | 0.87 | CSNK1D (0.53) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4458533 | 0.84 | NPC1 (0.59) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23273787 | 0.84 | NPC1 (0.50) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4452888 | 0.82 | ADORA1 (0.50) | CSNK1DNCS1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |