Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PHGDH | O43175 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887126 | 1.00 | KMT2A (0.74) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4455860 | 0.87 | PHGDH (0.77) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL13886982 | 0.87 | PHGDH (0.77) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL13611615 | 0.86 | MAPT (0.72) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4462860 | 0.86 | MAPT (0.72) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4326725 | 0.85 | MEN1 (1.00) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4326729 | 0.85 | MEN1 (1.00) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL13611475 | 0.84 | MAPT (0.71) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4341230 | 0.84 | KMT2A (0.68) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL4341235 | 0.84 | KMT2A (0.68) | KMT2AMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |