Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL29786754 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL4449154 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL31452874 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL18420918 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Hexanoate SCHEMBL6440248 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL916529 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Adipic Acid SCHEMBL6685723 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL8399877 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Adipic Acid SCHEMBL8369794 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL29714861 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043609-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | EASTMAN CHEMICAL COMPANY (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4263662-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | Eastman Chemical Company (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116745339-A | Novel thermoplastic polyesters and their synthesis | 伊士曼化工公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| WO-2022133001-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | EASTMAN CHEMICAL COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022124058-A1 | POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE | 株式会社ブリヂストン | 2022-06-16 | — | — | WO | disclosed |
| CN-109563252-B | Polyester compositions comprising tetramethylcyclobutanediol and ethylene glycol using an improved catalyst system | 伊士曼化工公司 | 2022-04-26 | — | — | CN | disclosed |
| EP-1958980-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORP (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20090270525-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1958980-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |