Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7714206 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL29628841 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL2381190 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Zinc Ion SCHEMBL676384 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL10889532 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL5164711 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4454263 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL11141761 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL4454306 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL11146203 | 0.95 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445277-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORP (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-7060757-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2006-06-13 | — | — | US | disclosed |
| US-20040220351-A1 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION | 2004-11-04 | — | — | US | disclosed |
| EP-1445277-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2004-08-11 | — | — | EP | disclosed |