Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812583 | 0.80 | EPHX2 (0.46) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14313766 | 0.74 | GRIN2D (0.50) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5804293 | 0.70 | GRIN2D (0.52) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3085164 | 0.70 | EPHX2 (0.46) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23367161 | 0.69 | — | — | |
| Cyclopentene SCHEMBL9743127 | 0.69 | EPHX2 (0.36) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4035388 | 0.66 | GRIN2D (0.52) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27857578 | 0.65 | EPHX2 (0.41) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12093024 | 0.64 | EPHX2 (0.33) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12093025 | 0.64 | EPHX2 (0.58) | EPHX2EPHX1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054314-A1 | Combined use of DPP-IV inhibitors and gastrin compounds | WARATAH PHARMACEUTICALS INC. (CA) | 2009-02-26 | — | — | US | disclosed |