SCHEMBL4454763

SCHEMBL4454763

CCC(N)c1ccc(C(=O)OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.58
MAPT P10636 2/20 0.55
LOXL2 Q9Y4K0 1/20 0.53
HPGD P15428 1/20 0.51
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA7 P43166 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TSHR P16473 1/20 0.47
STAT3 P40763 1/20 0.47
ALDH1A1 P00352 1/20 0.46
SLC6A4 P31645 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
STS P08842 1/20 0.45
CYP4A11 Q02928 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550245 1.00 DPP4 (0.58) DPP4MAPTLOXL2HPGDCA1
Hydrochloric Acid SCHEMBL987792 0.98 DPP4 (0.57) DPP4MAPTLOXL2HPGDCA1
SCHEMBL14550338 0.86 DPP4 (0.56) DPP4MAPTLOXL2HPGDCA1
SCHEMBL12326223 0.86 DPP4 (0.56) DPP4MAPTLOXL2HPGDCA1
SCHEMBL14551918 0.86 DPP4 (0.58) DPP4MAPTLOXL2HPGDCA1
SCHEMBL12584158 0.86 DPP4 (0.58) DPP4MAPTLOXL2HPGDCA1
SCHEMBL28444518 0.86 DPP4 (0.58) DPP4MAPTLOXL2HPGDCA1
SCHEMBL1739890 0.86 DPP4 (0.58) DPP4MAPTLOXL2HPGDCA1
Hydrochloric Acid SCHEMBL31269587 0.84 DPP4 (0.57) DPP4MAPTLOXL2HPGDCA1
Hydrochloric Acid SCHEMBL28694343 0.84 DPP4 (0.57) DPP4MAPTLOXL2HPGDCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481899-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN The University of Massachusetts (US) 2019-05-15 EP claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
WO-2018008003-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS (US) 2018-01-11 WO claimed
EP-3481899-B1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN UNIV MASSACHUSETTS (US) 2022-12-21 EP disclosed
US-10913844-B2 Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin THE UNIVERSITY OF MASSACHUSETTS (US) 2021-02-09 US disclosed
US-20190309159-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS 2019-10-10 US disclosed
EP-3481899-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN The University of Massachusetts (US) 2019-05-15 EP disclosed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN disclosed
WO-2018008003-A1 PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN THE UNIVERSITY OF MASSACHUSETTS (US) 2018-01-11 WO disclosed
WO-2016021742-A1 HETEROCYCLIC COMPOUNDS AS EP4 RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-02-11 WO disclosed
EP-2350020-B1 SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS MERCK SHARP & DOHME (US) 2014-08-13 EP disclosed
US-20090036495-A1 Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists PFIZER, INC. 2009-02-05 US disclosed
US-7238714-B2 Aryl or heteroaryl amide compounds PFIZER JAPAN, INC. (JP) 2007-07-03 US disclosed
EP-1740211-A2 COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS Pfizer Products Incorporated (US) 2007-01-10 EP disclosed
CN-1867551-A Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists PFIZER (US) 2006-11-22 CN disclosed
EP-1663979-A1 PHENYL OR PYRIDYL AMIDE COMPOUNDS AS PROSTAGLANDIN E2 ANTAGONISTS PFIZER INC. (US) 2006-06-07 EP disclosed
WO-2005102389-A2 COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS PFIZER PRODUCTS INC. (US) 2005-11-03 WO disclosed
WO-2005102389-A2 COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS PFIZER PRODUCTS INC. (US) 2005-11-03 WO disclosed
US-20050065188-A1 Aryl or heteroaryl amide compounds ASKAT INC. (JP) 2005-03-24 US disclosed
WO-2005021508-A1 PHENYL OR PYRIDYL AMIDE COMPOUNDS AS PROSTAGLANDIN E2 ANTAGONISTS PFIZER INC. (US) 2005-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065188-A1 Aryl or heteroaryl amide compounds HRH2, PTGER1, LTB4R2 DPP4 2357/4885MAPT 3996/4885LOXL2 433/4885
US-20090036495-A1 Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists PTGER4, PTGER2, OPRL1 DPP4 583/4885MAPT 4187/4885LOXL2 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.