Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | LCLAT1 | Q6UWP7 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783901 | 1.00 | CCR3 (0.51) | CCR3POLBACSS2RHOACASR | |
| SCHEMBL4454800 | 1.00 | CCR3 (0.51) | CCR3POLBACSS2RHOACASR | |
| SCHEMBL13783923 | 0.87 | CCR3 (0.47) | CCR3POLBACSS2RHOACASR | |
| SCHEMBL13783974 | 0.80 | CCR3 (0.51) | CCR3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4564936 | 0.77 | KDM4E (0.44) | CCR3POLBLCLAT1ALDH1A1MAPT | |
| SCHEMBL4564938 | 0.77 | KDM4E (0.44) | CCR3POLBLCLAT1ALDH1A1MAPT | |
| SCHEMBL4452740 | 0.76 | MAPT (0.49) | POLBRHOAMEN1ALDH1A1MAPT | |
| SCHEMBL4452736 | 0.76 | MAPT (0.49) | POLBRHOAMEN1ALDH1A1MAPT | |
| SCHEMBL4460394 | 0.74 | MAPT (0.61) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4460386 | 0.74 | MAPT (0.61) | POLBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |