SCHEMBL4454856

SCHEMBL4454856

c1ccc2c(P(CCCCCP(c3cccc4ccccc34)c3cccc4ccccc34)c3cccc4ccccc34)cccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ALDH1A1 P00352 5/20 0.39
TSHR P16473 4/20 0.39
HSD17B10 Q99714 4/20 0.39
RECQL P46063 1/20 0.39
CYP2A6 P11509 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
HPGD P15428 2/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15657844 1.00 CYP1A2 (0.41) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL15657780 1.00 CYP1A2 (0.41) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL11129209 0.98 CYP1A2 (0.42) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL8051835 0.94 CYP1A2 (0.42) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL15656388 0.91 KCNH2 (0.42) CYP1A2CYP2C19ALDH1A1TDP1HPGD
SCHEMBL15658677 0.91 KCNH2 (0.42) CYP1A2CYP2C19ALDH1A1TDP1HPGD
SCHEMBL11125323 0.89 CYP1A2 (0.45) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL5038026 0.89 TLR8 (0.39) CYP1A2CYP2C19CYP2C9ALDH1A1TDP1
SCHEMBL15658685 0.86 HTR1B (0.40) CYP1A2CYP2C19CYP2C9CA12CA3
SCHEMBL15656855 0.82 KCNH2 (0.38) CYP1A2CYP2C19ALDH1A1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156763-A1 Process for manufacturing a thermoplastic elastomeric material PIRELLI & C. S.P.A. (IT) 2009-06-18 US claimed
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
US-20090156763-A1 Process for manufacturing a thermoplastic elastomeric material PIRELLI & C. S.P.A. (IT) 2009-06-18 US disclosed
EP-0341773-B1 Process for the preparation of lactones SHELL INT RESEARCH (NL) 1996-09-11 EP disclosed
EP-0293053-B1 PROCESS FOR THE PREPARATION OF CYCLIC CARBOXYLIC ANHYDRIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-04 EP disclosed
US-4960906-A Process for the preparation of lactones from higher alkenols SHELL OIL COMPANY (US) 1990-10-02 US disclosed
EP-0227160-B1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-11 EP disclosed
EP-0121965-B1 PROCESS FOR THE PREPARATION OF POLYKETONES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-12-27 EP disclosed
EP-0341773-A1 Process for the preparation of lactones SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-11-15 EP disclosed
US-4849542-A Process for the preparation of oxo-alkanedioic acids or diesters thereof SHELL OIL COMPANY (US) 1989-07-18 US disclosed
US-4835250-A GROUP 8 METAL COMPLEX CATALYST SHELL OIL COMPANY (US) 1989-05-30 US disclosed
US-4818810-A USING POLYMERIZATION CATALYST OF REACTION PRODUCT OF GROUP EIGHT COMPOUND, LIGAND AND ACID SHELL OIL COMPANY (US) 1989-04-04 US disclosed
EP-0181014-B1 PROCESS FOR THE PREPARATION OF POLYKETONES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-11-30 EP disclosed
EP-0293053-A2 Process for the preparation of cyclic carboxylic anhydrides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-11-30 EP disclosed
EP-0227160-A2 Process for the carbonylation of ethylenically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-07-01 EP disclosed