SCHEMBL445487

SCHEMBL445487

COC(=O)c1ccc(OCCNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.64
CA2 P00918 6/20 0.64
CA12 O43570 5/20 0.64
CA9 Q16790 5/20 0.64
MAPT P10636 2/20 0.62
RAB9A P51151 2/20 0.56
NPC1 O15118 3/20 0.50
USP2 O75604 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
PDK2 Q15119 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MTNR1A P48039 1/20 0.49
MTNR1B P49286 1/20 0.49
POLB P06746 1/20 0.48
CASP3 P42574 1/20 0.48
SENP7 Q9BQF6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7490983 0.96 CA12 (0.65) CA1CA2CA12CA9MAPT
SCHEMBL15856116 0.92 CA12 (0.66) CA1CA2CA12CA9MAPT
SCHEMBL17162111 0.90 CA12 (0.60) CA1CA2CA12CA9MAPT
SCHEMBL17960659 0.88 CA12 (0.60) CA1CA2CA12CA9MAPT
SCHEMBL5152100 0.87 CA12 (0.66) CA1CA2CA12CA9MAPT
SCHEMBL1606333 0.87 TSHR (0.67) CA1CA2CA12CA9RAB9A
SCHEMBL21601467 0.87 CA12 (0.69) CA1CA2CA12CA9RAB9A
SCHEMBL4082188 0.86 MAPT (0.59) CA1CA2CA12CA9MAPT
SCHEMBL13191680 0.86 CA12 (0.54) CA1CA2CA12CA9MAPT
SCHEMBL5779176 0.86 CA12 (0.54) CA1CA2CA12CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054132-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-03-13 WO disclosed
US-20240342340-A1 MULTILAYER STRUCTURE USING CHEMICALLY CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2024-10-17 US disclosed
US-20240174772-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2024-05-30 US disclosed
US-11932708-B2 Crosslinked alginic acid MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2024-03-19 US disclosed
EP-4268856-A1 MULTILAYER STRUCTURE USING CHEMICALLY CROSSLINKED ALGINIC ACID Mochida Pharmaceutical Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-4268856-A1 MULTILAYER STRUCTURE USING CHEMICALLY CROSSLINKED ALGINIC ACID Mochida Pharmaceutical Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-4268855-A1 TRANSPLANTATION DEVICE USING CHEMICALLY CROSSLINKED ALGINIC ACID Mochida Pharmaceutical Co., Ltd. (JP) 2023-11-01 EP disclosed
US-20230035986-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-02-02 US disclosed
US-20230035986-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-02-02 US disclosed
US-20220409773-A1 TRANSPLANTATION DEVICE USING CHEMICALLY CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-12-29 US disclosed
US-5977124-A β-adrenergic agonists PFIZER INC. (US) 1999-11-02 US disclosed
US-5929120-A Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption MERCK & CO., INC. (US) 1999-07-27 US disclosed
US-5741796-A Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption MERCK & CO., INC. (US) 1998-04-21 US disclosed
EP-0828712-A1 BETA-ADRENERGIC AGONISTS PFIZER INC. (US) 1998-03-18 EP disclosed
EP-0824519-A1 BETA-ADRENERGIC AGONISTS PFIZER INC. (US) 1998-02-25 EP disclosed
EP-0760658-A4 COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION MERCK & CO INC (US) 1997-09-17 EP disclosed
EP-0760658-A1 COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION MERCK & CO. INC. (US) 1997-03-12 EP disclosed
WO-1996035671-A1 β-ADRENERGIC AGONISTS PFIZER INC. (US) 1996-11-14 WO disclosed
WO-1996035670-A1 β-ADRENERGIC AGONISTS PFIZER INC. (US) 1996-11-14 WO disclosed
WO-1995032710-A1 COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION MERCK & CO., INC. (US) 1995-12-07 WO disclosed