⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911630 | 0.80 | — | — | |
| SCHEMBL10541133 | 0.80 | — | — | |
| SCHEMBL140788 | 0.78 | — | — | |
| SCHEMBL1110971 | 0.78 | — | — | |
| SCHEMBL1006386 | 0.72 | — | — | |
| SCHEMBL10544835 | 0.70 | TSHR (0.36) | — | |
| SCHEMBL6595292 | 0.70 | — | — | |
| SCHEMBL2427968 | 0.70 | — | — | |
| SCHEMBL9535944 | 0.70 | — | — | |
| SCHEMBL1187296 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106554363-B | A kind of preparation method of Baricitinib intermediate | 正大天晴药业集团股份有限公司 | 2019-03-05 | — | — | CN | claimed |
| CN-106554363-A | A kind of preparation method of Baricitinib intermediates | 正大天晴药业集团股份有限公司 | 2017-04-05 | — | — | CN | claimed |
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | CHATTOPADHYAYA JYOTI (SE) | 2004-07-22 | — | — | US | claimed |
| EP-1332150-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | Chattopadhyaya, Jyoti (SE) | 2003-08-06 | — | — | EP | claimed |
| WO-2003039523-A2 | OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES | EXIQON A/S (DK) | 2003-05-15 | — | — | WO | claimed |
| WO-2002038578-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | CHATTOPADHYAYA JYOTI (SE) | 2002-05-16 | — | — | WO | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| US-4248618-A | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | claimed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-11964957-B2 | Pyrazole derivative and harmful organism-controlling agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| EP-3808738-B1 | PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-117645642-A | Compounds for RNA capping and uses thereof | 广州市恒诺康医药科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2000075157-A1 | OLIGONUCLEOTIDE SYNTHESIS WITH LEWIS ACIDS AS ACTIVATORS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |
| EP-0889885-A1 | METHOD FOR SELECTIVE PROTECTION OF BACCATIN DERIVATIVES AND ITS APPLICATION TO TAXANE SYNTHESIS | Societé d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm (FR) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997024345-A1 | METHOD FOR SELECTIVE PROTECTION OF BACCATIN DERIVATIVES AND ITS APPLICATION TO TAXANE SYNTHESIS | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 1997-07-10 | — | — | WO | disclosed |
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |
| US-4742073-A | ANTIGLAUCOMA | BUNDGAARD HANS (DK) | 1988-05-03 | — | — | US | disclosed |
| EP-0106541-A2 | Pilocarpine prodrugs | Bundgaard, Hans (DK) | 1984-04-25 | — | — | EP | disclosed |