Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519180 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7516424 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL942766 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL16335520 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL608444 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3180403 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL200253 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL10758355 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11136407 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7513498 | 0.95 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090189127-A1 | Optical resin lens and production method for optical resin material | KONICA MINOLTA OTPO, INC. (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-0463464-B1 | Process for the preparation of 2-chloro-5-methylpyridine | BAYER AG (DE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0463464-A1 | Process for the preparation of 2-chloro-5-methylpyridine | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |