Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455367 | 0.86 | EGFR (0.58) | EGFR | |
| SCHEMBL4445055 | 0.80 | EGFR (0.53) | EGFR | |
| SCHEMBL4446912 | 0.79 | EGFR (0.67) | EGFR | |
| SCHEMBL13604777 | 0.79 | EGFR (0.69) | EGFR | |
| SCHEMBL4455210 | 0.78 | EGFR (0.82) | EGFR | |
| SCHEMBL4446919 | 0.78 | EGFR (0.75) | EGFR | |
| SCHEMBL4455376 | 0.78 | EGFR (0.68) | EGFR | |
| SCHEMBL4446915 | 0.77 | EGFR (0.60) | EGFR | |
| SCHEMBL6009190 | 0.77 | EGFR (0.71) | EGFR | |
| SCHEMBL4449418 | 0.77 | EGFR (0.62) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632840-B2 | Quinazoline compounds for the treatment of hyperproliferative disorders | ASTRAZENECA AB (SE) | 2009-12-15 | — | — | US | disclosed |