Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22462185 | 0.95 | CYP3A4 (0.61) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL6779063 | 0.95 | CYP3A4 (0.61) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL163444 | 0.85 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL1537285 | 0.85 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL29183811 | 0.84 | CYP3A4 (0.58) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| Hydrochloric Acid SCHEMBL28331180 | 0.83 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL28504890 | 0.83 | CYP3A4 (0.57) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL28328192 | 0.82 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL5221763 | 0.81 | CYP3A4 (0.65) | CYP3A4SLC7A5HRH4HRH3MEN1 | |
| SCHEMBL27759486 | 0.81 | CYP3A4 (0.65) | CYP3A4SLC7A5HRH4HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017007-A1 | LIQUID FACTOR VII COMPOSITION | MAXYGEN HOLDINGS LTD. | 2009-01-15 | — | — | US | claimed |
| EP-1919498-A2 | LIQUID FACTOR VII COMPOSITION | Maxygen Holdings Ltd. (KY) | 2008-05-14 | — | — | EP | claimed |
| WO-2007022784-A2 | LIQUID FACTOR VII COMPOSITION | MAXYGEN HOLDINGS LTD. (KY) | 2007-03-01 | — | — | WO | claimed |