Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63676 | 1.00 | PLA2G4B (0.50) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31093484 | 0.99 | PLA2G4B (0.49) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29396017 | 0.95 | PLA2G4B (0.46) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29465911 | 0.95 | PLA2G4B (0.46) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL225850 | 0.93 | PLA2G4B (0.44) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL183916 | 0.92 | PLA2G4B (0.46) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL1056070 | 0.90 | PLA2G4B (0.42) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL5713078 | 0.89 | S1PR1 (0.48) | PLA2G4BS1PR1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL30555138 | 0.89 | PLA2G4B (0.41) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL30555112 | 0.89 | PLA2G4B (0.41) | PLA2G4BS1PR1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137576-B1 | DUAL PHOTOINITIATOR, PHOTOCURABLE COMPOSITION, USE THEREOF AND PROCESS FOR PRODUCING A THREE DIMENSIONAL ARTICLE | 3D SYSTEMS INCORPORATED (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-2076563-A1 | THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS | Ciba Holding Inc. (CH) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008049743-A1 | THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS | CIBA HOLDING INC. (CH) | 2008-05-02 | — | — | WO | disclosed |