SCHEMBL4456910

SCHEMBL4456910

COC1CCC(OC)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.33
DPP4 P27487 1/20 0.32
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700 1.00
SCHEMBL18773606 1.00 EPHX2 (0.33) EPHX2DPP4DAO
SCHEMBL9393516 1.00 EPHX2 (0.33) EPHX2DPP4DAO
Ammonia Solution, Strong SCHEMBL8083382 0.96
Hydrochloric Acid SCHEMBL1163215 0.96
Hydrochloric Acid SCHEMBL16990138 0.92
SCHEMBL4547601 0.89 EPHX2 (0.31) EPHX2
SCHEMBL17547398 0.89 EPHX2 (0.31) EPHX2
SCHEMBL12235366 0.86
SCHEMBL17546177 0.86 CA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230148372-A1 Degradable, Printable Poly(Propylene Fumarate)-Based ABA Triblock Elastomers DUKE UNIVERSITY (US) 2023-05-11 US claimed
US-8252846-B2 Strategies for delivery of active agents using micelles and particles EMORY UNIVERSITY (US) 2012-08-28 US claimed
EP-0366700-B1 ELECTRICAL WIRE RAYCHEM LIMITED (GB) 1993-01-27 EP claimed
EP-0275591-B1 PROCESS FOR THE SELECTIVE OXIDATIVE CARBONYLATION OF CONJUGATED DIENES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-01-29 EP claimed
EP-0366700-A1 ELECTRICAL WIRE. RAYCHEM LTD (GB) 1990-05-09 EP claimed
US-4868328-A Selective oxidative carbonylation of conjugated dienes SHELL OIL COMPANY (US) 1989-09-19 US claimed
WO-1989000761-A1 ELECTRICAL WIRE RAYCHEM LIMITED (GB) 1989-01-26 WO claimed
EP-0275591-A2 Process for the selective oxidative carbonylation of conjugated dienes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-27 EP claimed
US-12034115-B2 Solid electrolyte composition, sheet for all-solid state secondary battery, electrode sheet for all-solid state secondary battery, and all-solid state secondary battery FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
CN-118255975-A Light-responsive polycarbonate copolymer and preparation method thereof 中国石油天然气股份有限公司 2024-06-28 CN disclosed
US-20240213479-A1 ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND MANUFACTURING METHODS FOR ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, AND ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed
EP-4314107-A1 STORAGE STABLE THERMOSETTING POWDER COATING COMPOSITIONS COMPRISING AN EPOXY CROSSLINKER AND A POLYESTER RESIN PREPARED FROM CITRIC ACID AND/OR CITRIC ACID ANHYDRIDE, AND POWDER COATINGS THEREOF HAVING AT LEAST GOOD CHEMICAL RESISTANCE AND AT LEAST VERY GOOD ADHESION Covestro (Netherlands) B.V. (NL) 2024-02-07 EP disclosed
US-20240025902-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF EGFR AND RELATED METHODS OF USE BEONE MEDICINES I GMBH (CH) 2024-01-25 US disclosed
CN-117015563-A Storage-stable thermosetting powder coating composition comprising an epoxy crosslinker and a polyester resin prepared from citric acid and/or citric anhydride, and powder coating thereof with at least good chemical resistance and at least very good adhesion 科思创(荷兰)有限公司 2023-11-07 CN disclosed
WO-1989000759-A1 WIRE RAYCHEM LIMITED (GB) 1989-01-26 WO disclosed
WO-1989000761-A1 ELECTRICAL WIRE RAYCHEM LIMITED (GB) 1989-01-26 WO disclosed
EP-0275591-A2 Process for the selective oxidative carbonylation of conjugated dienes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-27 EP disclosed
US-4431621-A USING A POLYHYDROXY COMPOUND TO CONTROL POROSITY; RECOVERING SNAMPROGETTI S.P.A. (IT) 1984-02-14 US disclosed
US-4414272-A SILICA, EPOXIDE, SILANE COUPLER OR ORGANOTITANIUM COMPOUND TEIJIN LIMITED (JP) 1983-11-08 US disclosed
EP-0048481-A2 Shaped polyester composite material having an activated surface thereof and process for producing the same TEIJIN LIMITED (JP) 1982-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025902-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF EGFR AND RELATED METHODS OF USE EGFR, ERBB2, CBL EPHX2 1330/4885DPP4 3114/4885DAO 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.