Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.54 |
| ▸ | ABL1 | P00519 | 5/20 | 0.54 |
| ▸ | BCR | P11274 | 4/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ABL2 | P42684 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | STK25 | O00506 | 1/20 | 0.46 |
| ▸ | CIT | O14578 | 1/20 | 0.46 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | CASK | O14936 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.46 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892020 | 0.86 | SRC (0.76) | SRCABL1BCRRIPK2EGFR | |
| SCHEMBL13938749 | 0.72 | SRC (0.86) | SRCABL1BCR | |
| SCHEMBL3228158 | 0.71 | SRC (0.69) | SRCABL1BCR | |
| SCHEMBL22861713 | 0.70 | SRC (1.00) | SRCABL1BCRABL2 | |
| SCHEMBL1897734 | 0.68 | SRC (0.80) | SRCABL1BCRRIPK2EGFR | |
| SCHEMBL5260184 | 0.68 | SRC (0.58) | SRCABL1BCR | |
| SCHEMBL3990230 | 0.67 | SRC (0.84) | SRCABL1BCR | |
| SCHEMBL2978588 | 0.67 | SRC (0.84) | SRCABL1BCREGFRABL2 | |
| SCHEMBL4967200 | 0.67 | SRC (0.84) | SRCABL1BCR | |
| SCHEMBL5255575 | 0.67 | SRC (0.84) | SRCABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151910-A2 | COMBINATION PRODUCT OF RECEPTOR TYROSINE KINASE INHIBITOR AND FATTY ACID SYNTHASE INHIBITOR FOR TREATING CANCER | WYETH (US) | 2009-12-17 | — | — | WO | disclosed |