SCHEMBL4457895

SCHEMBL4457895

CNC(C)(O)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295786 0.76
SCHEMBL2208007 0.76
Bromide SCHEMBL442644 0.73
Hydrochloric Acid SCHEMBL28467082 0.73
Hydrochloric Acid SCHEMBL68105 0.73
SCHEMBL6717 0.70
Tert-Butanol SCHEMBL7521629 0.70
Dimethylamine SCHEMBL21838384 0.70
SCHEMBL9005249 0.70
SCHEMBL27402279 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10100002-B2 Method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether from a mixture HUNTSMAN INTERNATIONAL LLC (US) 2018-10-16 US claimed
EP-3057937-A1 METHOD FOR SEPARATING N,N,N'-TRIMETHYLBISAMINOETHYLETHER AND/OR N,N-DIMETHYLBISAMINOETHYLETHER FROM A MIXTURE Huntsman Corporation Hungary ZRt. (HU) 2016-08-24 EP claimed
US-20160237024-A1 Method for Separating N,N,N'-Trimethylbisaminoethylether and/or N,N-Dimethylbisaminoethylether from a Mixture Huntsman Corporation Hungary ZRt (HU) 2016-08-18 US claimed
WO-2015055406-A1 METHOD FOR SEPARATING N,N,N'-TRIMETHYLBISAMINOETHYLETHER AND/OR N,N-DIMETHYLBISAMINOETHYLETHER FROM A MIXTURE HUNTSMAN CORPORATION HUNGARY ZRT. (HU) 2015-04-23 WO claimed
EP-2862851-A1 Method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether from a mixture Huntsman Corporation Hungary ZRt. (HU) 2015-04-22 EP claimed
US-20260085059-A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE SERVIER PHARMACEUTICALS LLC (US) 2026-03-26 US disclosed
WO-2025046121-A1 LIPID NANOPARTICLE WITH NUCLEIC ACID CARGO AND IONIZABLE LIPID NOVOARC GMBH (AT) 2025-03-06 WO disclosed
US-20240335450-A1 TABLET COMPOSITIONS CELGENE CORP (US) 2024-10-10 US disclosed
US-20240132474-A1 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE SERVIER PHARMACEUTICALS LLC (US) 2024-04-25 US disclosed
CN-110372670-B Therapeutically active compounds and methods of use thereof 法国施维雅药厂 2023-04-07 CN disclosed
EP-4147692-A1 COMBINATION THERAPY FOR TREATING MALIGNANCIES Les Laboratoires Servier (FR) 2023-03-15 EP disclosed
US-20220323447-A1 TABLET COMPOSITIONS CELGENE CORP (US) 2022-10-13 US disclosed
WO-2015017821-A2 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE AGIOS PHARMACEUTICALS, INC. (US) 2015-02-05 WO disclosed
US-20090005567-A1 PROCESS FOR THE PREPARATION OF 4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO (5,6)-CYCLOHEPTA-(1,2B) -PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER (LORATADINE) ZACH SYSTEM S.P.A. (IT) 2009-01-01 US disclosed
US-7449583-B2 Process for the preparation of 4-(8-chloro-5 6-dihydro-11h-benzo-(5 6)-cyclohepta-(1 2b)-pyridin-11-ylidene-1-piperidiniecarboxylic acid ethyl ester (loratadine) ZACH SYSTEM S.P.A. (IT) 2008-11-11 US disclosed
EP-1442035-B1 PROCESS FOR THE PREPARATION OF 4- (8-CHLORO-5, 6-DIHYDRO-11H-BENZO-[5,6]-CYCLOHEPTA-[1,2-B]-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER (LORATADINE) ZAMBON SPA (IT) 2006-01-11 EP disclosed
US-20050171352-A1 Process for the preparation of 4-(8-chloro-5 6-dihydro-11h-benzo-(5 6)-cyclohepta-(1 2b)-pyridin-11-ylidene-1-piperidiniecarboxylic acid ethyl ester (loratadine) ZAMBON GROUP S.P.A (IT) 2005-08-04 US disclosed
EP-1442035-A1 PROCESS FOR THE PREPARATION OF 4- (8-CHLORO-5, 6-DIHYDRO-11H-BENZO-[5,6]-CYCLOHEPTA-[1,2-B]-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER (LORATADINE) ZAMBON GROUP S.p.A. (IT) 2004-08-04 EP disclosed
US-20030148624-A1 Method for removing resists MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-08-07 US disclosed
WO-2003040140-A1 PROCESS FOR THE PREPARATION OF 4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO(5,6)-CYCLOHEPTA-(1,2B)-PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLI C ACID ETHYL ESTER (LORATADINE) ZAMBON GROUP S.P.A. (IT) 2003-05-15 WO disclosed