SCHEMBL4458181

SCHEMBL4458181

O=C(O)C1O[C@@H]1C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10574077 1.00
SCHEMBL1331676 1.00
SCHEMBL4466386 1.00
SCHEMBL1331675 1.00
SCHEMBL28237722 1.00 SUCNR1 (1.00)
SCHEMBL253521 1.00
SCHEMBL516367 0.96 SUCNR1 (0.92)
SCHEMBL31300476 0.96 SUCNR1 (0.92)
Potassium SCHEMBL515336 0.96 SUCNR1 (0.92)
SCHEMBL28559430 0.96 SUCNR1 (0.92)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3648689-A2 OXIDATIVE COMPOSITIONS AND METHODS FOR STIMULATING THE GROWTH OF OSTEOBLASTS AND USE IN DENTAL COATINGS AND JAW BONE AUGMENTATION Armis Biopharma, Inc. (US) 2020-05-13 EP disclosed
WO-2019010467-A2 OXIDATIVE COMPOSITIONS AND METHODS FOR STIMULATING THE GROWTH OF OSTEOBLASTS AND USE IN DENTAL COATINGS AND JAW BONE AUGMENTATION ARMIS BIOPHAMA, INC. (US) 2019-01-10 WO disclosed
US-8673904-B2 Epoxide inhibitors of cysteine proteases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-03-18 US disclosed
US-8673904-B2 Epoxide inhibitors of cysteine proteases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-03-18 US disclosed
EP-2056758-A2 EPOXY-CONTAINING POLY(ESTER AMIDES) AND METHODS OF USE Medivas, LLC (US) 2009-05-13 EP disclosed
US-20080176841-A1 EPOXIDE INHIBITORS OF CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-07-24 US disclosed
US-20080176841-A1 EPOXIDE INHIBITORS OF CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-07-24 US disclosed
WO-2008042480-A2 EPOXIDE INHIBITORS OF CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-04-10 WO disclosed
WO-2008021548-A2 EPOXY-CONTAINING POLY(ESTER AMIDES) AND METHODS OF USE MEDIVAS, LLC (US) 2008-02-21 WO disclosed
WO-2007087572-A2 AZA-PEPTIDE EPOXIDES GEORGIA TECH RESEARCH CORPORATION (US) 2007-08-02 WO disclosed
WO-2004005270-A1 AZA-PEPTIDE EPOXIDES GEORGIA TECH RESEARCH CORPORATION (US) 2004-01-15 WO disclosed
EP-0722456-A1 ANTIFUNGAL COMPOSITIONS BTG INTERNATIONAL LIMITED (GB) 1996-07-24 EP disclosed
WO-1995009867-A1 ANTIFUNGAL COMPOSITIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-04-13 WO disclosed
US-4863916-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed