Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189213 | 0.93 | PIK3CG (0.54) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL13416234 | 0.89 | PIK3CG (0.52) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL13452395 | 0.88 | PIK3CG (0.55) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL4341568 | 0.88 | PIK3CG (0.54) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL189182 | 0.87 | PIK3CG (0.61) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL188854 | 0.87 | PIK3CG (0.56) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL189852 | 0.87 | PIK3CG (0.55) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL189067 | 0.86 | PIK3CG (0.53) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL189059 | 0.86 | PIK3CG (0.53) | PIK3CGPIK3CDMEN1KMT2APIK3CA | |
| SCHEMBL189365 | 0.85 | PIK3CG (0.52) | PIK3CGPIK3CDMEN1KMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |