Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2369439 | 0.84 | ERCC1 (0.52) | ALDH1A1ERCC1FEN1ERCC4TSHR | |
| Acetic Acid SCHEMBL28464649 | 0.82 | ERCC1 (0.50) | ALDH1A1ERCC1FEN1ERCC4TSHR | |
| SCHEMBL29361703 | 0.81 | ERCC1 (0.62) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| SCHEMBL1410 | 0.81 | ERCC1 (0.62) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| SCHEMBL710689 | 0.81 | ERCC1 (0.62) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| SCHEMBL1279494 | 0.79 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| Ammonia Solution, Strong SCHEMBL8656352 | 0.79 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| Lithium SCHEMBL1279496 | 0.79 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| SCHEMBL2824834 | 0.79 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4NPC1 | |
| Water SCHEMBL4444794 | 0.79 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538084-B2 | Cyclosporins | AMR TECHNOLOGY, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1603512-A2 | NOVEL CYCLOSPORINS | Albany Molecular Research, Inc. (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040235716-A1 | Novel cyclosporins | CURIA GLOBAL, INC. | 2004-11-25 | — | — | US | disclosed |
| WO-2004082629-A2 | NOVEL CYCLOSPORINS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235716-A1 | Novel cyclosporins | CHP1, IL2, CCR1 | ALDH1A1 2632/4885ERCC1 1082/4885FEN1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.