Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341966 | 0.92 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4455738 | 0.88 | IGF1R (1.00) | IGF1R | |
| SCHEMBL12653098 | 0.82 | IGF1R (0.82) | IGF1R | |
| SCHEMBL4456120 | 0.82 | IGF1R (1.00) | IGF1R | |
| SCHEMBL11340802 | 0.81 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4461050 | 0.81 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4455819 | 0.79 | IGF1R (0.79) | IGF1R | |
| SCHEMBL14050435 | 0.79 | IGF1R (0.84) | IGF1R | |
| SCHEMBL11338910 | 0.78 | IGF1R (1.00) | IGF1R | |
| SCHEMBL13213687 | 0.77 | IGF1R (0.79) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |