Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677156 | 0.88 | PTPN1 (0.51) | PTPN1HDAC8MMP8MMP3NPSR1 | |
| SCHEMBL32676714 | 0.88 | PTPN1 (0.51) | PTPN1HDAC8MMP8MMP3NPSR1 | |
| SCHEMBL29798976 | 0.88 | PTPN1 (0.51) | PTPN1HDAC8MMP8MMP3NPSR1 | |
| SCHEMBL2730308 | 0.88 | PTPN1 (0.51) | PTPN1HDAC8MMP8MMP3NPSR1 | |
| SCHEMBL8736850 | 0.86 | POLB (0.41) | PTPN1HDAC8NPSR1MAPTPOLB | |
| SCHEMBL32676857 | 0.84 | PTPN1 (0.46) | PTPN1NPSR1POLBMEN1KMT2A | |
| SCHEMBL32677157 | 0.84 | PTPN1 (0.46) | PTPN1NPSR1POLBMEN1KMT2A | |
| SCHEMBL21902981 | 0.82 | POLB (0.38) | PTPN1HDAC8MMP8MMP3NPSR1 | |
| SCHEMBL15054567 | 0.81 | POLB (0.51) | POLBTDP1L3MBTL1 | |
| SCHEMBL15054569 | 0.81 | POLB (0.51) | POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058065-A1 | BORONATES AS ARGINASE INHIBITORS | MARS INCORPORATED (US) | 2012-05-03 | — | — | WO | disclosed |