Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL8571521 | 1.00 | TSHR (0.80) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Dodecane SCHEMBL28692851 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL8524874 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Decane SCHEMBL28433575 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL15875086 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hexane SCHEMBL8499715 | 0.95 | TSHR (0.70) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hentriacontane SCHEMBL3661625 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Nonane SCHEMBL7178862 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL6056456 | 0.95 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL16178970 | 0.90 | TSHR (0.80) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121907-A2 | ALKANE OXIDATION BY MODIFIED HYDROXYLASES | The California Institute of Technology (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008098198-A2 | ALKANE OXIDATION BY MODIFIED HYDROXYLASES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-08-14 | — | — | WO | disclosed |
| EP-1899471-A2 | ALKANE OXIDATION BY MODIFIED HYDROXYLASES | The California Institute of Technology (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006105082-A2 | ALKANE OXIDATION BY MODIFIED HYDROXYLASES | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-10-05 | — | — | WO | disclosed |