Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.65 |
| ▸ | PTPRF | P10586 | 1/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478559 | 0.86 | PTPN1 (0.79) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4459365 | 0.85 | PTPN1 (0.68) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4468241 | 0.82 | PTPN1 (0.58) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5743653 | 0.82 | PTPN1 (0.83) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4267561 | 0.81 | PTPN1 (0.63) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4464574 | 0.81 | PTPN1 (0.67) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4465013 | 0.80 | PTPN1 (0.60) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7497194 | 0.79 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4462498 | 0.79 | PTPN1 (0.71) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3867351 | 0.78 | PTPN1 (0.77) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525365-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620422-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| US-20050004369-A1 | Phenyl substituted carboxylic acids | INSTITUTES FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | claimed |
| WO-2004099170-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| US-7524878-B2 | Phenyl substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICALS DISCOVERY LLC (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524878-B2 | Phenyl substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICALS DISCOVERY LLC (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524878-B2 | Phenyl substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICALS DISCOVERY LLC (US) | 2009-04-28 | — | — | US | disclosed |
| US-20050004369-A1 | Phenyl substituted carboxylic acids | INSTITUTES FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004369-A1 | Phenyl substituted carboxylic acids | PTPA, PTPRS, PTPRO | PTPN1 18/4885PTPRF 11/4885PTPRA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.