Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.68 |
| ▸ | CTSL | P07711 | 2/20 | 0.65 |
| ▸ | CTSB | P07858 | 2/20 | 0.65 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.65 |
| ▸ | F3 | P13726 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460729 | 1.00 | CHRNA7 (0.68) | CHRNA7CTSLCTSBCAPN1F3 | |
| SCHEMBL23610336 | 0.86 | TYR (0.64) | CHRNA7CTSLCTSBCAPN1MAPT | |
| SCHEMBL471834 | 0.86 | TYR (0.64) | CHRNA7CTSLCTSBCAPN1MAPT | |
| SCHEMBL9341622 | 0.83 | MAPT (0.58) | MEN1MAPTKMT2AMAOB | |
| SCHEMBL9341614 | 0.83 | MAPT (0.58) | MEN1MAPTKMT2AMAOB | |
| SCHEMBL633002 | 0.82 | PTPN1 (0.66) | CHRNA7CTSLCTSBCAPN1F3 | |
| SCHEMBL30559523 | 0.82 | PTPN1 (0.66) | CHRNA7CTSLCTSBCAPN1F3 | |
| SCHEMBL29929014 | 0.82 | PTPN1 (0.66) | CHRNA7CTSLCTSBCAPN1F3 | |
| SCHEMBL633001 | 0.82 | PTPN1 (0.66) | CHRNA7CTSLCTSBCAPN1F3 | |
| SCHEMBL1695380 | 0.81 | CHRNA7 (1.00) | CHRNA7CTSLCTSBCAPN1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744732-A4 | NUTRITIONAL COMPOSITION FOR INCREASING CREATINE UPTAKE IN SKELETAL MUSCLE | THERMO FORMULATIONS LTD (CA) | 2009-08-26 | — | — | EP | disclosed |
| EP-1744732-A2 | NUTRITIONAL COMPOSITION FOR INCREASING CREATINE UPTAKE IN SKELETAL MUSCLE | Thermo Formulations Ltd. (CA) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110448-A2 | NUTRITIONAL COMPOSITION FOR INCREASING CREATINE UPTAKE IN SKELETAL MUSCLE | THERMO FORMULATIONS LTD. (CA) | 2005-11-24 | — | — | WO | disclosed |