SCHEMBL446080

SCHEMBL446080

C=C(C(=O)OCCCN)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.32
CPB2 Q96IY4 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ODC1 P11926 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033345 0.94 TSHR (0.42) TSHRCYP1A2THRBCPB2POLB
SCHEMBL19207251 0.93 TSHR (0.44) TSHRCYP1A2THRBCPB2POLB
SCHEMBL19207299 0.93 TSHR (0.44) TSHRCYP1A2THRBCPB2POLB
SCHEMBL19207246 0.93 TSHR (0.44) TSHRCYP1A2THRBCPB2POLB
SCHEMBL19207268 0.93 TSHR (0.44) TSHRCYP1A2THRBCPB2POLB
SCHEMBL19207302 0.93 TSHR (0.44) TSHRCYP1A2THRBCPB2POLB
SCHEMBL41031 0.88 TSHR (0.36) TSHRTHRB
Ammonia Solution, Strong SCHEMBL3663515 0.86 TSHR (0.35) TSHRTHRB
Hydrochloric Acid SCHEMBL2533776 0.86 TSHR (0.35) TSHRTHRB
Chloromethane SCHEMBL543091 0.85 TSHR (0.34) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155833-A1 ADDITIVE TO REDUCE FLUID LOSS FOR DRILLING FLUIDS 3M Innovative Properties Company (US) 2010-02-24 EP claimed
WO-2008156970-A1 ADDITIVE TO REDUCE FLUID LOSS FOR DRILLING FLUIDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-12-24 WO claimed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP claimed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO claimed
WO-1999002610-A1 UV CURABLE COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-01-21 WO claimed
EP-0517373-B1 Method for making structured suspension PSA beads MINNESOTA MINING & MFG (US) 1996-12-04 EP claimed
US-5464916-A Pressure sensitive adhesive, acrylic ester polymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-07 US claimed
EP-0517373-A1 Method for making structured suspension PSA beads MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-12-09 EP claimed
US-4335028-A STABLE AQUEOUS SOLUTIONS OR DISPERSIONS SCM CORPORATION (US) 1982-06-15 US claimed
EP-2968090-B1 METHOD OF REMOVING POLYMERIZED COATINGS FROM HUMAN NAILS, POLYMERIZED COATING FOR HUMAN NAILS HAVING IMPROVED REMOVABILITY, AND TWO PACKAGE SYSTEM MYCONE DENTAL SUPPLY COMPANY INC (US) 2021-06-02 EP disclosed
US-10722093-B2 Cleaning article 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-07-28 US disclosed
US-20190203081-A1 FLUORINATED PRESSURE SENSITIVE ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY 2019-07-04 US disclosed
EP-3497174-A1 FLUORINATED PRESSURE SENSITIVE ADHESIVE 3M Innovative Properties Company (US) 2019-06-19 EP disclosed
CN-108474183-A Cation surface sizing agent 凯米罗总公司 2018-08-31 CN disclosed
US-4198495-A ISOBUTOXYMETHYL ACRYLAMIDE OR METHACRYLAMIDE, UNSATURATED MONOMER HAVING BASIC AMINO GROUP, NEUTRALIZED WITH SOLUBILIZING ACID DESOTO, INC. (US) 1980-04-15 US disclosed
US-4195147-A ADDING AMINE-FUNCTIONAL MONOMER TO HEATED HEEL OF WATER-MISCIBLE SOLVENT CONTAINING SOLUBILIZING ACID DESOTO, INC. (US) 1980-03-25 US disclosed
US-4172062-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy-amine adducts DESOTO, INC. (US) 1979-10-23 US disclosed
US-4085020-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy-amine adducts DESOTO, INC. (US) 1978-04-18 US disclosed
US-4036800-A Electrodeposition of aqueous dispersions of amine functional urethane copolymers DESOTO, INC. (US) 1977-07-19 US disclosed
US-4033917-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy-amine adducts DESOTO, INC. (US) 1977-07-05 US disclosed