SCHEMBL446127

SCHEMBL446127

CCNC=CNCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446126 1.00
SCHEMBL19886275 1.00
SCHEMBL23169923 0.86
SCHEMBL11965022 0.86
SCHEMBL14401579 0.86
SCHEMBL25041243 0.83
SCHEMBL23170315 0.83
SCHEMBL25129335 0.83
SCHEMBL18978021 0.83
SCHEMBL2566993 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9700627-B2 Biodegradable poly (beta-amino esters) and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-07-11 US claimed
US-20160022821-A1 BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-28 US claimed
EP-2923692-B1 Beta-amino ester compounds and uses thereof LIVING PROOF INC (US) 2018-05-30 EP disclosed
EP-1828354-B1 HYDROCARBYL SUCCINIC ACID AND HYDROCARBYLSUCCINIC ACID DERIVATIVES AS FRICTION MODIFIERS BASF SE (DE) 2017-09-06 EP disclosed
US-9700627-B2 Biodegradable poly (beta-amino esters) and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-07-11 US disclosed
US-9486497-B2 Treatment of immunocompromised conditions THE UNIVERSITY OF QUEENSLAND (AU) 2016-11-08 US disclosed
US-20160193294-A1 COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2016-07-07 US disclosed
US-20160022821-A1 BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-28 US disclosed
US-20160002406-A1 BETA-AMINO ESTER COMPOUNDS AND USES THEREOF LIVING PROOF, INC. (US) 2016-01-07 US disclosed
US-9175114-B2 Beta-amino ester compounds and uses thereof LIVING PROOF, INC. (US) 2015-11-03 US disclosed
EP-2923692-A1 Beta-amino ester compounds and uses thereof Living Proof, Inc. (US) 2015-09-30 EP disclosed
EP-1639029-A2 BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF Massachusetts Institute of Technology (US) 2006-03-29 EP disclosed
US-6998115-B2 Biodegradable and biocompatible and may be used in a variety of drug delivery systems; suited for the delivery of polynucleotides MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-02-14 US disclosed
US-20050265961-A1 Biodegradable poly(beta-amino esters) and uses thereof NATIONAL SCIENCE FOUNDATION 2005-12-01 US disclosed
WO-2004106411-A2 BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-12-09 WO disclosed
US-20040071654-A1 Biodegradable poly(beta-amino esters) and uses thereof NATIONAL SCIENCE FOUNDATION 2004-04-15 US disclosed
EP-1401918-A2 BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-03-31 EP disclosed
WO-2002031025-A9 BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INST TECHNOLOGY (US) 2003-05-30 WO disclosed
US-20020131951-A1 Biodegradable and biocompatible and may be used in a variety of drug delivery systems; suited for the delivery of polynucleotides NATIONAL SCIENCE FOUNDATION 2002-09-19 US disclosed
WO-2002031025-A2 BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-04-18 WO disclosed