SCHEMBL446180

SCHEMBL446180

CCCCCC[Si](C)(C)Cl

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.43
DNM1 Q05193 7/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121666 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL81296 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL12987948 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2120482 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2123927 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL20857010 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL367147 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL18406142 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL42043 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2121979 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841857-A Preparation method of pentamethyldisiloxane and preparation method of active silicone oil 江西晨光新材料股份有限公司 2025-04-18 CN claimed
CN-114341072-B Textured glass articles and methods of making the same 康宁股份有限公司 2023-11-14 CN claimed
CN-115418048-B Anti-shrinkage polypropylene furniture board composite material and preparation method thereof 浙江利帆家具有限公司 2023-09-26 CN claimed
CN-116284162-A Synthesis and preparation method of lycium barbarum acid 宁夏农林科学院农业资源与环境研究所(宁夏土壤与植物营养重点实验室) 2023-06-23 CN claimed
CN-115418048-A Anti-shrinkage polypropylene furniture board composite material and preparation method thereof 浙江利帆家具有限公司 2022-12-02 CN claimed
US-11485677-B2 Textured glass articles and methods of making the same CORNING INCORPORATED (US) 2022-11-01 US claimed
CN-114341072-A Textured glass article and method of making same 康宁股份有限公司 2022-04-12 CN claimed
CN-111804007-B Method for hydrophobizing hydrophilic materials 株式会社岛津制作所 2022-02-25 CN claimed
US-11090631-B2 Method for hydrophobization of hydrophilic material SHIMADZU CORPORATION (JP) 2021-08-17 US claimed
US-20200407270-A1 TEXTURED GLASS ARTICLES AND METHODS OF MAKING THE SAME CORNING INCORPORATED 2020-12-31 US claimed
WO-2010113188-A1 FLUORURATED SILICONIC POLYMER, SYNTHESIS METHOD AND USE MAFLON S.R.L. (IT) 2010-10-07 WO claimed
CN-101243061-A Processes for the preparation of docetaxel UNIV FLORIDA STATE RES FOUND (US) 2008-08-13 CN claimed
CN-101243060-A Processes for the preparation of paclitaxel UNIV FLORIDA STATE RES FOUND (US) 2008-08-13 CN claimed
CN-101243095-A Method for producing polycyclic fused ring compound UNIV FLORIDA STATE RES FOUND (US) 2008-08-13 CN claimed
CN-1247603-C Substituted metallocene compounds for olefin polymerization catalyst systems, their intermediates and methods for preparing them BOREALIS AS (DK) 2006-03-29 CN claimed
CN-1089342-C Heteroatom substituted metallocene compounds for olefin polymerization catalyst systems and methods for their preparation BOREALIS AS (DK) 2002-08-21 CN claimed
US-6365643-B1 Photoinitiators for cationic curing TH. GOLDSCHMIDT AG (DE) 2002-04-02 US claimed
EP-0937043-B1 NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SERVIER LAB (FR) 2002-03-06 EP claimed
CN-1255139-A Substituted metallocene compounds for olefin polymerization catalyst systems, their intermediates and methods for preparing them BOREALIS AS (DK) 2000-05-31 CN claimed
CN-1214687-A Heteroatom substituted metallocene compounds for polymerization catalyst system and method for preparing them BOREALIS AS (DK) 1999-04-21 CN claimed