SCHEMBL4463574

SCHEMBL4463574

CCCCC(CC)COP(=S)([S-])OCC(CC)CCCC.CCCCC(CC)COP(=S)([S-])OCC(CC)CCCC.[Cu+2]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 7/20 0.41
CA2 P00918 3/20 0.37
RECQL P46063 1/20 0.36
LMNA P02545 2/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP14 P50281 1/20 0.34
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19837261 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL8610580 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL3781028 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL6693742 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL9076587 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL9322673 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL8365435 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL7557219 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
Zinc Ion SCHEMBL166463 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL9584869 0.96 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304274-B1 Chlorine-containing resin compositions DAINIPPON INK & CHEMICALS (JP) 1993-12-22 EP claimed
EP-0304274-A2 Chlorine-containing resin compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-02-22 EP claimed
JP-1131267-A None JP disclosed
EP-1445277-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORP (JP) 2009-01-07 EP disclosed
EP-0945488-B1 Rubber composition BRIDGESTONE CORP (JP) 2006-12-27 EP disclosed
US-7060757-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2006-06-13 US disclosed
US-20040220351-A1 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION 2004-11-04 US disclosed
EP-1445277-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORPORATION (JP) 2004-08-11 EP disclosed
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
EP-0945488-A2 Rubber composition Bridgestone Corporation (JP) 1999-09-29 EP disclosed
US-5939493-A NATURAL RUBBER OR DIENE SYNTHETIC RUBBER, METAL DITHIOPHOSPHATE, TERTIARY AMINE; REINFORCING INORGANIC FILLER BRIDGESTONE CORPORATION (JP) 1999-08-17 US disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed
EP-0864604-A2 Rubber composition Bridgestone Corporation (JP) 1998-09-16 EP disclosed
EP-0304274-B1 Chlorine-containing resin compositions DAINIPPON INK & CHEMICALS (JP) 1993-12-22 EP disclosed
EP-0444830-A1 Succinimide composition ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1991-09-04 EP disclosed
EP-0201903-B1 PHOTOPOLYMERIZABLE COMPOSITION MITSUBISHI RAYON CO., LTD. (JP) 1991-08-07 EP disclosed
JP-H01131267-A COLORANT COMPOSITION FOR CHLORINE-CONTAINING RESIN AND CHLORINE-CONTAINING RESIN COMPOSITION DAINIPPON INK & CHEM INC 1989-05-24 JP disclosed
EP-0304274-A2 Chlorine-containing resin compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-02-22 EP disclosed