Methane

Methane

SCHEMBL4464140

C.C.C.C.C.NC([O-])=S.NC([O-])=S.[Zn+2]

nearest known ligand 0.46

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
ATR Q13535 1/20 0.46
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
PTGS2 P35354 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.31
LDHA P00338 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL1502804 1.00 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL27385044 1.00 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Zinc Ion SCHEMBL59923 0.95
Zinc Ion SCHEMBL23500196 0.90 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL3283415 0.90 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
Methane SCHEMBL8628684 0.90
Methane SCHEMBL15252312 0.90 TSHR (0.46) TSHRATMATRALDH1A1HSD17B10
SCHEMBL1275553 0.89 TSHR (0.56) TSHRATMATRALDH1A1HSD17B10
Ethane SCHEMBL298477 0.86 TSHR (0.42) TSHRATMATRALDH1A1HSD17B10
Ethylene SCHEMBL27532034 0.86 TSHR (0.42) TSHRATMATRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108633280-B Crosslinked foams made from ethylene/alpha-olefin interpolymers 陶氏环球技术有限责任公司 2021-03-26 CN disclosed
US-8356647-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2013-01-22 US disclosed
US-20090242094-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-10-01 US disclosed
US-20010036983-A1 Inhibiting discoloration of halogen-containing polymers after radiation OCCIDENTAL CHEMICAL CORPORATION. 2001-11-01 US disclosed
EP-0494156-B1 ROOF SHEETING AND FLASHING ELASTOMERIC COMPOSITION UNIROYAL CHEM CO INC (US) 1994-10-19 EP disclosed
EP-0385053-B1 Method for production of linoleum MONDO SPA (IT) 1994-07-27 EP disclosed
EP-0494156-A1 ROOF SHEETING AND FLASHING ELASTOMERIC COMPOSITION. UNIROYAL CHEM CO INC (US) 1992-07-15 EP disclosed
WO-1991005012-A1 ROOF SHEETING AND FLASHING ELASTOMERIC COMPOSITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1991-04-18 WO disclosed
EP-0385053-A2 Method for production of linoleum MONDO S.p.A. (IT) 1990-09-05 EP disclosed