SCHEMBL4464460

SCHEMBL4464460

O=S(=O)(O)C1=CC=CCC1=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7341448 0.81
SCHEMBL7818004 0.79
SCHEMBL10359724 0.79 SMN1; SMN2 (0.33)
SCHEMBL587839 0.77
SCHEMBL3301824 0.73
SCHEMBL425783 0.73
SCHEMBL4225062 0.72
SCHEMBL9069582 0.72
SCHEMBL6938661 0.72
SCHEMBL1526040 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119040628-A Efficient green gold leaching agent and application method thereof 中南大学 2024-11-29 CN claimed
EP-3808768-A1 CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION Pfizer Inc. (US) 2021-04-21 EP claimed
US-20190030183-A1 CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION PFIZER INC. (US) 2019-01-31 US claimed
WO-2018146585-A1 LARGE SCALE PRODUCTION PROCESS FOR CAPPED AND UN-CAPPED ANTIBODY CYSTEINES AND THEIR USE IN THERAPEUTIC PROTEIN CONJUGATION PFIZER INC. (US) 2018-08-16 WO claimed
EP-3334760-A2 CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION Pfizer Inc (US) 2018-06-20 EP claimed
WO-2017025897-A2 CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION PFIZER INC. (US) 2017-02-16 WO claimed
EP-0474861-B1 ALCOHOL-ESTER SEPARATION BY REACTION WITH ACETATE EASTMAN CHEM CO (US) 1994-09-14 EP claimed
EP-0474853-B1 PROTECTED HYDROXY METHOD FOR ALCOHOL-ESTER SEPARATION EASTMAN CHEM CO (US) 1994-08-10 EP claimed
EP-0244167-B1 IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1990-04-04 EP claimed
CN-120289420-A Method for realizing thiosulfate alkylation based on micro-flow field technology 南京工业大学 2025-07-11 CN disclosed
CN-119040628-A Efficient green gold leaching agent and application method thereof 中南大学 2024-11-29 CN disclosed
CN-119040628-A Efficient green gold leaching agent and application method thereof 中南大学 2024-11-29 CN disclosed
US-12121588-B2 Large scale production process for capped and un-capped antibody cysteines and their use in therapeutic protein conjugation PFIZER INC. (US) 2024-10-22 US disclosed
US-11980669-B2 Capped and uncapped antibody cysteines, and their use in antibody-drug conjugation PFIZER, INC. (US) 2024-05-14 US disclosed
WO-2017025897-A2 CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION PFIZER INC. (US) 2017-02-16 WO disclosed
US-20150175634-A1 Preparation of Phenol- or Thiophenyl-Sulfonic Acid Functionalized Solid Acids NATIONAL TAIWAN UNIVERSITY (TW) 2015-06-25 US disclosed
US-9062081-B1 Preparation of phenol- or thiophenyl-sulfonic acid functionalized solid acids NATIONAL TAIWAN UNIVERSITY (TW) 2015-06-23 US disclosed
EP-2049476-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZaCh System S.p.A. (IT) 2009-04-22 EP disclosed
WO-2008012268-A1 PROCESS FOR THE PREPARATION OF LEVETIRACETAM ZACH SYSTEM S.P.A. (IT) 2008-01-31 WO disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed