Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472323 | 0.87 | DPP4 (0.50) | DPP4CHRM1 | |
| SCHEMBL4472053 | 0.86 | DPP4 (0.44) | DPP4KCNH2 | |
| SCHEMBL4252797 | 0.86 | DPP4 (0.39) | DPP4KCNH2CHRM1 | |
| SCHEMBL4252796 | 0.86 | DPP4 (0.39) | DPP4KCNH2CHRM1 | |
| SCHEMBL4479698 | 0.86 | DPP4 (0.54) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4479704 | 0.86 | DPP4 (0.54) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4475888 | 0.85 | DPP4 (0.47) | DPP4 | |
| SCHEMBL4480411 | 0.82 | DPP4 (0.53) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL4465821 | 0.82 | DPP4 (0.53) | DPP4KCNH2CHRM1FAP | |
| SCHEMBL13936198 | 0.81 | DPP4 (0.55) | DPP4KCNH2CHRM1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495002-B2 | 3-methyl-7-butinyl-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-24 | — | — | US | disclosed |
| US-20060079541-A1 | 3-methyl-7-butinyl-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079541-A1 | 3-methyl-7-butinyl-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP7, DPP3 | DPP4 1/4885KCNH2 2767/4885CHRM1 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.