Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464708 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL4459973 | 0.84 | CYP1A2 (0.39) | CYP2C19ACACBKMT2AALDH1A1KDM4E | |
| SCHEMBL4459962 | 0.84 | CYP1A2 (0.39) | CYP2C19ACACBKMT2AALDH1A1KDM4E | |
| SCHEMBL13645754 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL7719250 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL7718204 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL13645867 | 0.69 | HTT (0.46) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL21655203 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL14779934 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 | |
| SCHEMBL13645758 | 0.67 | HTT (0.44) | SMN1; SMN2PKMHTTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |