Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464954 | 1.00 | TP53 (0.45) | TP53TSHRMAPTCCR1SMN1; SMN2 | |
| SCHEMBL842686 | 1.00 | TP53 (0.45) | TP53TSHRMAPTCCR1SMN1; SMN2 | |
| SCHEMBL842685 | 1.00 | TP53 (0.45) | TP53TSHRMAPTCCR1SMN1; SMN2 | |
| SCHEMBL842268 | 0.87 | TP53 (0.48) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL842267 | 0.87 | TP53 (0.48) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL842534 | 0.85 | TP53 (0.46) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL842533 | 0.85 | TP53 (0.46) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL842299 | 0.82 | TP53 (0.44) | TP53MAPTCCR1SMN1; SMN2YAP1 | |
| SCHEMBL4328417 | 0.74 | HPGD (0.45) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4324743 | 0.72 | TP53 (0.49) | TP53MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152474-A2 | PROCESS FOR THE PREPARATION OF (3S)-3-AMINO-N-CYCLOPROPYL-2-HYDROXYALKANAMIDE DERIVATIVES | VIROBAY, INC. (US) | 2009-12-17 | — | — | WO | disclosed |