Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730832 | 1.00 | TLR7 (0.58) | TLR7IL6 | |
| SCHEMBL4459455 | 0.90 | TLR7 (0.58) | TLR7IL6 | |
| SCHEMBL729563 | 0.90 | TLR7 (0.58) | TLR7IL6 | |
| SCHEMBL729582 | 0.90 | TLR7 (0.58) | TLR7IL6 | |
| SCHEMBL731247 | 0.89 | TLR7 (0.61) | TLR7IL6 | |
| SCHEMBL728849 | 0.88 | TLR7 (0.65) | TLR7 | |
| SCHEMBL730725 | 0.88 | TLR7 (0.60) | TLR7IL6 | |
| SCHEMBL734225 | 0.88 | TLR7 (0.64) | TLR7 | |
| SCHEMBL731534 | 0.87 | TLR7 (0.63) | TLR7 | |
| SCHEMBL729606 | 0.87 | TLR7 (0.65) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041135-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | Astra Zeneca AB (SE) | 2009-04-01 | — | — | EP | claimed |
| WO-2008004948-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | claimed |
| EP-2041135-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | Astra Zeneca AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008004948-A1 | 8-OXOADENINE DERIVATIVES ACTING AS MODULATORS OF TLR7 | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |