Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 7/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CCND2 | P30279 | 3/20 | 0.43 |
| ▸ | CCND3 | P30281 | 3/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13605302 | 0.91 | MCHR1 (0.50) | MCHR1RIPK2NOD2CSNK2A1CDK4 | |
| SCHEMBL1734449 | 0.85 | MCHR1 (0.53) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL13605280 | 0.83 | MCHR1 (0.51) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL1736441 | 0.82 | MCHR1 (0.53) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL1735219 | 0.81 | RIPK2 (0.44) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL1735255 | 0.81 | CSNK2A1 (0.60) | MCHR1RIPK2NOD2CSNK2A1CDK4 | |
| SCHEMBL1735257 | 0.80 | MCHR1 (0.59) | MCHR1RIPK2NOD2CSNK2A1CDK4 | |
| SCHEMBL13605370 | 0.79 | HRH3 (0.52) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL4462748 | 0.78 | HRH3 (0.49) | MCHR1RIPK2NOD2CDK4CCND1 | |
| SCHEMBL13605338 | 0.78 | MCHR1 (0.46) | MCHR1RIPK2NOD2CSNK2A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514447-B2 | Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors | IRM LLC (BM) | 2009-04-07 | — | — | US | disclosed |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | KIT, PRKCH, PRKCE | MCHR1 1115/4885RIPK2 2205/4885NOD2 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.