⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562714 | 0.75 | — | — | |
| SCHEMBL1562715 | 0.75 | — | — | |
| SCHEMBL1562737 | 0.75 | — | — | |
| SCHEMBL424257 | 0.73 | — | — | |
| SCHEMBL424258 | 0.69 | — | — | |
| SCHEMBL67264 | 0.68 | — | — | |
| SCHEMBL8397539 | 0.68 | — | — | |
| SCHEMBL5432 | 0.68 | — | — | |
| SCHEMBL9191756 | 0.67 | — | — | |
| SCHEMBL23169287 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121372-B1 | ADENINE DERIVATIVES | PFIZER LTD (GB) | 2006-06-28 | — | — | EP | claimed |
| US-6326359-B1 | PURINE DERIVATIVES | PFIZER INC | 2001-12-04 | — | — | US | claimed |
| EP-1121372-A1 | ADENINE DERIVATIVES | Pfizer Limited (GB) | 2001-08-08 | — | — | EP | claimed |
| WO-2000023457-A1 | ADENINE DERIVATIVES | PFIZER LIMITED (GB) | 2000-04-27 | — | — | WO | claimed |
| EP-2041120-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008007930-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2008-01-17 | — | — | WO | disclosed |
| EP-1121372-B1 | ADENINE DERIVATIVES | PFIZER LTD (GB) | 2006-06-28 | — | — | EP | disclosed |
| US-6326359-B1 | PURINE DERIVATIVES | PFIZER INC | 2001-12-04 | — | — | US | disclosed |
| EP-0688312-B1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LAB (IT) | 1998-11-18 | — | — | EP | disclosed |
| US-5723494-A | Derivatives of glutamic and aspartic acids, a method of preparing them, and their use as drugs for enhancing memory and learning | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1998-03-03 | — | — | US | disclosed |
| EP-0688312-A1 | NEW DERIVATIVES OF GLUTAMIC ACID, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020454-A1 | NEW DERIVATIVES OF GLUTAMIC AND ASPARTIC ACIDS, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS FOR ENHANCING MEMORY AND LEARNING | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1994-09-15 | — | — | WO | disclosed |