⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7000189 | 0.97 | — | — | |
| SCHEMBL1043762 | 0.74 | — | — | |
| SCHEMBL28904963 | 0.70 | — | — | |
| SCHEMBL15291273 | 0.69 | GRM5 (0.50) | — | |
| Acetonitrile SCHEMBL8129305 | 0.65 | — | — | |
| SCHEMBL18867911 | 0.64 | GRM5 (1.00) | — | |
| SCHEMBL6123248 | 0.63 | GRM5 (0.46) | — | |
| SCHEMBL9794492 | 0.62 | GRM5 (0.44) | — | |
| SCHEMBL7964249 | 0.61 | TSHR (0.50) | — | |
| SCHEMBL1763216 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330907-A | Method for synthesizing thiazole derivative by taking carbon disulfide, ammonia gas and monochloroacetone as raw materials | 江苏诺恩作物科学股份有限公司 | 2025-01-21 | — | — | CN | claimed |
| EP-3571198-B1 | BICYCLIC AMINES AS JAK KINASE INHIBITORS | LEO PHARMA AS (DK) | 2023-02-01 | — | — | EP | claimed |
| CN-115362149-A | SHP2 inhibitor and composition and application thereof | 贝达药业股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-110291090-A | Bentyl as novel jak kinase inhibitor | 利奥制药有限公司 | 2019-09-27 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| WO-2019016834-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF THIABENDAZOLE | HIKAL LIMITED (IN) | 2019-01-24 | — | — | WO | claimed |
| CN-107667107-A | Ethynyl derivatives serving | 豪夫迈·罗氏有限公司 | 2018-02-06 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| US-9469741-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | claimed |
| EP-2203482-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORP (JP) | 2015-11-25 | — | — | EP | claimed |
| EP-1196401-A1 | METHOD FOR PRODUCING 2-AMINOMETHYL-4-CYANO-THIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | claimed |
| EP-1196402-A1 | METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | claimed |
| WO-2001007425-A1 | METHOD FOR PRODUCING 2-AMINOMETHYL-4-CYANO-THIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007426-A1 | METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | claimed |
| WO-1994025458-A1 | PREPARATION OF HIGH PURITY THIABENDAZOLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-10 | — | — | WO | claimed |
| WO-1994025457-A1 | PROCESS FOR PREPARING THIABENDAZOLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-10 | — | — | WO | claimed |
| US-5310923-A | From 4-cyanothiazole and o-phenylenediamine, acid catalyst, solvent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| US-5310924-A | Acid-catalyzed condensation of 4-cyanothiazole and o-phenylenediamine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| EP-0045654-A1 | Catalyst for the preparation of 4-cyanothiazole | MERCK & CO. INC. (US) | 1982-02-10 | — | — | EP | claimed |
| US-4010173-A | FROM B,B-DICHLORO-ALPHA-AMINO-ACRYLONITRILE AND A THIOAMIDE, ACID CATALYST | MERCK & CO., INC. (US) | 1977-03-01 | — | — | US | claimed |