SCHEMBL4466622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4473898	0.87	CDK1 (0.68)	CDK2CDK1CA12CA1CA2
	SCHEMBL4467252	0.84	CDK2 (0.64)	CDK2CDK1CA12CA1CA2
	SCHEMBL13918111	0.83	IKBKB (0.54)	CDK2CDK1CA12CA1CA2
	SCHEMBL13932210	0.83	CDK2 (0.48)	CDK2CDK1CA2CA9HTT
	SCHEMBL4466637	0.83	CDK2 (0.65)	CDK2CDK1CA12CA1CA2
	Gw831090X SCHEMBL4465882	0.83	CDK2 (0.65)	CDK2CDK1CA12CA1CA2
	SCHEMBL4470268	0.82	CDK2 (0.67)	CDK2CDK1CA1CA2CA9
	SCHEMBL5510994	0.81	CA12 (0.50)	CDK2CDK1CA12CA1CA2
	SCHEMBL4471046	0.80	MEN1 (0.61)	CDK2CDK1CA12CA1CA2
	SCHEMBL4466766	0.77	CDK2 (0.62)	CDK2CDK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.